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Rough endoplasmic reticulum (rER) in a plasma cell

Microimage
EM image of a plasma cell Image copyright: University of Oslo, CC BY-NC-ND 4.0.

Rough endoplasmic reticulum (rER) and Golgi complexes are characteristic of cells with high protein synthesis for export. In this case, it involves immunoglobulins (antibodies), which are not stored in the cell prior to secretion. The eccentrically placed nucleus contains a large amount of condensed chromatin, organized in clusters near the cell membrane. A prominent nucleolus and the nucleus’s double membrane (difficult to see here) are also noteworthy. The cytoplasm is filled with abundant rER. Additionally, at least one Golgi complex and several mitochondria are visible. There are also small vesicles (membrane-bound sacs near the cell membrane), which may represent the transport of completed immunoglobulins to the cell membrane, where they are secreted via exocytosis. The cell membrane is clearly visible.

Try to identify the following structures:

  • Cell nucleus
  • Nucleolus
  • Condensed chromatin
  • Extended chromatin
  • Nuclear membrane
  • rER
  • Golgi apparatus
  • Mitochondria
  • Vesicles (with immunoglobulin?)
  • Cell membrane