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The marginal zone of the white pulp (400X)

Microimage
The marginal zone of the white pulp in the human spleen. Image copyright: University of Oslo, CC BY-NC-ND 4.0. (Tissue stain: H+E).

At the interface between the red and white pulps lies the marginal zone, which contains a mixture of lymphocytes, macrophages, and dendritic cells. This zone acts as a site for antigen capture and initiation of the immune response, facilitating interactions between blood-borne antigens and immune cells.

Published June 10th 2023, updated July 3rd 2024.